Hu Anti-NKX3.1 IgG

Product name

Anti-Nkx3.1 antibody [EPR14970]


Rabbit monoclonal [EPR14970] to Nkx3.1

Host species


Proven applications

Suitable for: WB, IHC-P

Species reactivity

Reacts with: Human


Recombinant fragment. This information is the property of Abcam and/or its suppliers.

Positive control

Human prostate tissue

General notes

This product is a recombinant monoclonal antibody, offering several benefits including:

– High reproducibility and consistency from batch to batch
– Improved sensitivity and specificity
– Long-term security of supply
– Animal-free production


1. Form


2. Storage instructions

Shipped at 4 ° C. Store at + 4 ° C for short term (1-2 weeks). At the time of delivery aliquot. Store at -20 ° C long term. Avoid the freeze/thaw cycle.

3. Storage buffer

  • pH: 7.2
  • Preservative: 0.01% sodium azide
  • Components: 59% PBS, 40% glycerol (glycerin, glycerin), 0.05% BSA

4. Concentration

100 µl to 1,193 mg / ml

5. Purity

Purified Protein A

6. Clonality


7. Cloning number


8. Isotype



Transcription factor, which preferentially binds to the consensus sequence 5′-TAAGT [AG] -3 ‘and can behave as a transcriptional repressor. They play an important role in the normal development of the prostate, regulating the proliferation of the glandular epithelium and in the formation of ducts in the prostate. It acts as a tumor suppressor by controlling prostate carcinogenesis, as evidenced by the ability to inhibit the proliferation and invasion activities of PC-3 prostate cancer cells.

Tissue specificity

Highly expressed in the prostate and, to a lesser extent, in the testes.

Sequence similarities

  • It belongs to the NK-3 homeobox family.
  • Contains 1 homeobox DNA-binding domain.

Post-translational modifications

Ubiquitinado by TOPORS; monoubiquitinated at various residues and also polyubiquitinated at individual residues.

Cell location

  • Core.
  • Previous Destination Information for Access UniProt Q99801
  • The UniProt Consortium

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