PCDHB14 (protocadherin β14) belongs to the family of protocadherins. It is expressed mainly in the nervous system. It is located on chromosome 5.
Recombinant protein epitope signature tag of protocadherin beta 14 (perst)
All Prestige Powered by Atlas Antibodies antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org) and, as a result, are backed by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas.
Antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and diseased tissues and, through recent efforts by the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome. not only at the tissue level but now at the subcellular level. These images and the collection of this vast dataset can be viewed on the Human Protein Atlas (HPA) site by clicking the Image Gallery link. To view these protocols and other helpful information about Prestige Antibodies and HPA, visit sigma.com/prestige.
The solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.
Unless otherwise stated in our catalog or other company documentation accompanying the product (s), our products are intended for research use only and are not to be used for any other purpose, including but not limited to commercial uses. unauthorized, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses, or any type of consumption or application to humans or animals.
Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC
Biochemical / Physiological Actions
PCDHB14 (protocadherin β14) can participate in the establishment of neuronal connections and in the transduction of signals in the synaptic membrane.
Features and Benefits
Prestige Antibodies are highly characterized and widely validated antibodies with the added benefit that all available characterization data for each target is accessible through the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of Prestige Antibodies with other proteins are due to careful selection of antigenic regions, affinity purification, and rigorous selection. Prestige Antigen Controls are available for each corresponding Prestige Antibody and can be found in the links section.
Each Prestige Antibody is tested in the following ways:
• IHC tissue matrix of 44 normal human tissues and 20 of the most common cancer-type tissues.
• Protein matrix of 364 recombinant human protein fragments.